Actively Recruiting
Psychiatric Multi-omics and Neuroimaging Project Database
Led by mingjun Zhong · Updated on 2026-03-13
1899
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to explore the structure and function of the brain along with gene expression in the blood of people with schizophrenia and other mental disorders. It seeks to discover biological markers and understand how genes and the environment affect brain networks related to these conditions. The study includes participants with schizophrenia, psychosis, major depressive disorder, autism spectrum disorder, bipolar disorder, and healthy individuals for comparison. Participants will continue their prescribed medications if they have mental disorders, while healthy individuals will not take any medicine. The study does not interfere with their usual treatment. Participants will be grouped based on their diagnosis or health status, including healthy controls and various mental disorder categories. During the study, participants will undergo baseline and follow-up assessments over one year. These assessments include brain imaging to measure cortical morphology (about 40 minutes), gene characteristic testing (about 1 day), and completing clinical scale questionnaires (about 90 minutes). The study carefully monitors participants without altering their treatment and collects data to better understand schizophrenia and related conditions.
CONDITIONS
Brief Title
Psychiatric Multi-omics and Neuroimaging Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 13 and 35 years old (for patients with healthy siblings, age can be 14 to 35 years)
- Disease duration less than 24 months
- Preference for patients who have never taken medication or have used medication for less than 2 weeks
- No contraindications for magnetic resonance imaging (MRI)
You will not qualify if you...
- Family history of psychotic disorders
- History of psychoactive substance abuse, alcohol dependence, or nicotine dependence
- Presence of major physical disease or infectious disease
- History of coma or serious neurological disease
- Contraindications for MRI
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo assessments including brain imaging, gene characteristic analysis, and clinical scale evaluations to gather data on psychiatric conditions.
1 visit (in-person)
Duration - Up to 5 years
Participants are observed over time to understand the biological markers and brain network changes related to psychiatric disorders without altering their prescribed medication regimen.
Additional assessments may occur depending on cohort assignment
Trial Site Locations
Total: 1 location
1
The Second Xiangya hospital of central south univerity
Changsha, Hunan, China, 410000
Actively Recruiting
Research Team
Y
Yunzhi Pan
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here