Actively Recruiting
Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
Led by Children's Hospital Medical Center, Cincinnati · Updated on 2026-01-08
75
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to understand the development and progression of childhood dystonia, a movement disorder, in children. The main questions it aims to answer are: How does the activity of the neural network evolve in children with dystonia in the context of motor development? What are the effects of chronic and active stimulation on cortical and subcortical motor network function in children with deep brain stimulation (DBS)? Participants will: * Undergo noninvasive electrophysiological measurements (EEG, EMG) to quantify neural network activity. They will be tested at rest and during a simple motor reaction task. * Children with DBS will be assessed in the on and off DBS state to assess effects of chronic and active changes in motor network function.
CONDITIONS
Official Title
Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- For dystonia subjects: diagnosis of dystonia (with or without DBS)
- Willingness and ability to complete study protocols
- For typically developing controls: normal developmental milestones
- No neuropsychiatric disorders
- No significant medical conditions
You will not qualify if you...
- History of epilepsy
- Presence of implanted medical devices (except DBS in dystonia subjects)
- Lack of cognitive or physical ability to complete study protocol
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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