Actively Recruiting
Observational Study of Patients with Oral Lichen Planus to Track Cancer Risk and Clinical Features
Led by Catholic University of the Sacred Heart · Updated on 2026-05-14
300
Participants Needed
1
Research Sites
52 weeks
Total Duration
AI-Summary
What this Trial Is About
Oral Lichen Planus OLP is a chronic inflammatory disease mainly affecting the mouths lining, caused by an immune response that damages the cells in the mouth. This research observes a group of patients with OLP over a long period to check how often their condition changes into oral cancer. It also aims to identify patient characteristics and risk factors linked to this transformation and to assess how well treatments for OLP work. The study looks back at medical records and clinical data of patients with OLP to examine their history and dental health, focusing on factors that may increase the risk of developing oral cancer. It does not involve new treatments but evaluates existing patient information to understand disease progression and treatment effects. Participants will be followed for at least six months, with researchers reviewing their clinical and dental records to gather data. The main measurement is the number of oral cancer cases identified from January 2024 to January 2028. This observational approach helps monitor long-term outcomes and characteristics without active intervention, with the study concluding in January 2029.
CONDITIONS
Brief Title
Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience
Research Team
C
Carlo Lajolo Associate Professor, DDS, MD, PhD
C
Carlo Lajolo Associate Professor, MD, DDS, PhD
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