Actively Recruiting
Regional Assessment of the Risk of Lung Injury in Ventilated Patients
Led by Hospital El Cruce · Updated on 2024-07-03
10
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Specific characteristics of the lung, such as its functional capacity, heterogeneity, and recruitment potential, can influence the development of ventilator-induced lung injury even under safe ventilation conditions. Objective: To evaluate the risk of ventilator-induced lung injury at the regional level in patients with acute respiratory distress syndrome ventilated with similar tidal volumes and inspiratory pressures.
CONDITIONS
Official Title
Regional Assessment of the Risk of Lung Injury in Ventilated Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of acute respiratory distress syndrome (ARDS)
You will not qualify if you...
- History of emphysema, asthma, pneumothorax, or active bronchopulmonary fistula
- Severe instability defined by SaO2 ≤ 90%, shock requiring > 0.5 γ/kg/min of noradrenaline, complex arrhythmia, myocardial ischemia, or refractory intracranial hypertension
- Esophageal conditions preventing esophageal balloon placement such as varices, stenosis, trauma, surgery, tumor, or hematemesis
- Severe coagulopathy with platelet count <20,000/mm3 or INR >4
- Inability to undergo computed tomography due to morbid obesity (>170 kg) or abdominal circumference >200 cm
- Presence of do-not-resuscitate orders
- Pregnancy
- Participation in another research study within the last 30 days
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital El Cruce
San Juan Bautista, Buenos Aires, Argentina, 1853
Actively Recruiting
Research Team
N
Nestor Pistillo, MD
CONTACT
O
Osvaldo Fariña, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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