Study of Gastric Preconditioning by Percutaneous Angioembolization Before Esophagectomy in Patients at High Risk of Anastomotic Leak

What this Trial Is About

Researchers are studying how often anastomotic leaks occur in patients who have esophageal cancer and are at high risk for these leaks. The study focuses on patients who are eligible for a procedure called gastric preconditioning by percutaneous angioembolization before they undergo esophagectomy, which is surgery to remove part or all of the esophagus. This research aims to better understand the risks associated with this approach in people with specific risk factors for leaks after surgery. Participants in this observational study will have gastric preconditioning using percutaneous angioembolization before their planned esophagectomy. The gastric preconditioning procedure is done prior to the esophagectomy to potentially reduce the risk of anastomotic leak. All participants will be people with esophageal malignancy who have a high risk of leakage and have agreed to receive this preconditioning. There are no requirements regarding prior treatments. During the study, researchers will monitor participants for the occurrence of anastomotic leaks for up to one year after surgery. They will collect information related to the surgery and outcomes to evaluate how often leaks happen in this high-risk group. Participants will be followed and assessed as part of routine care, with study data collected to understand the safety and incidence of leaks after this treatment approach. The total duration of follow-up is one year after the surgery.

Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak