Actively Recruiting
Retinal Imaging in Neurodegenerative Disease
Led by Duke University · Updated on 2026-02-04
2000
Participants Needed
1
Research Sites
493 weeks
Total Duration
On this page
Sponsors
D
Duke University
Lead Sponsor
U
University of Edinburgh in Scotland
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the retinal and choroidal microvasculature and structure in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD), or other neurodegenerative disease, diseases as outlined.
CONDITIONS
Official Title
Retinal Imaging in Neurodegenerative Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults diagnosed with neurodegenerative diseases such as Mild Cognitive Impairment, Parkinson's Disease, Alzheimer's Disease, Frontotemporal Dementia, Lewy Body Dementia, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Huntington Disease, Traumatic Brain Injury, concussion, Post-Traumatic Stress Disorder, or Down Syndrome
- Adults without neurodegenerative disease
You will not qualify if you...
- Inability to cooperate with or complete testing, or presence of other neurologic or age-related eye conditions that would affect image quality
- Eyes that have undergone intraocular surgery other than cataract surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Duke University Medical Center
Durham, North Carolina, United States, 27705
Actively Recruiting
Research Team
S
Sharon Fekrat, MD FACS FASRS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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