Retrospective Study on Long-Term Outcomes and Treatments of Early Gastric Cancer in Chinese Patients Using a National Database

What this Trial Is About

Researchers are studying early gastric cancer EGC patients in China to understand their clinical and pathological characteristics, how treatment methods affect long-term outcomes, and what factors influence prognosis. This retrospective observational study uses a large prospective clinical database to analyze about 5,000 patients diagnosed with early-stage gastric adenocarcinoma. The aim is to compare different treatment approaches and provide evidence to improve personalized care for EGC patients in China. The study collects detailed data on various treatment methods such as endoscopic resection, laparoscopic surgery, open surgery, and combined laparoscopic-endoscopic approaches. Treatment details, surgical complications, and pathological staging are gathered retrospectively from electronic medical records. Patients were treated primarily at Beijing Friendship Hospital, and data are extracted from the National Clinical Research Center for Digestive Diseases database. The study includes long-term follow-up extending up to 10 years after surgery to evaluate survival outcomes and recurrence patterns. Participants information includes baseline demographics, tumor characteristics, surgery details, and postoperative recovery data. Researchers assess disease-free survival as the primary outcome over a 10-year period after surgery. Secondary outcomes include overall survival, recurrence-free and progression-free survival, surgical complications within 30 days, and various laboratory and imaging assessments before and after surgery. Quality of life questionnaires and nutritional status markers are also tracked. This comprehensive data collection aims to provide insights into treatment safety and effectiveness, guiding future clinical decisions for early gastric cancer.

Retrospective Analysis of Early Gastric Cancer Patients Based on Prospective Clinical Dataset