Long-term Study of Recurrent Cervical Artery Dissection and Stroke Risk After Pregnancy in Women with Prior CeAD

What this Trial Is About

Researchers are investigating whether pregnancy increases the risk of recurrent cervical artery dissection CeAD and delayed stroke in women who have had a prior CeAD. This observational, multicenter case-control study collects long-term data from several stroke centers to better understand the relationship between pregnancy and CeAD recurrence. They also explore if delivery method influences recurrence and whether women chose to avoid future pregnancies due to the initial CeAD. The study compares two groups of women those who became pregnant at least once after their first CeAD and those who did not become pregnant afterward. Data is gathered through medical record reviews and patient interviews, covering long-term follow-up of at least six months with no upper time limit. Outcomes include recurrent CeAD, ischemic or hemorrhagic stroke, death, and functional status measured by the modified Rankin Scale. Participants provide information about pregnancy history and health outcomes during follow-up visits. Researchers assess the occurrence of recurrent CeAD, strokes, and death over periods up to 35 years from the initial event. They use statistical analysis to compare risks between women who became pregnant and those who did not. The study lasts until July 2025 and monitors functional outcomes as well as survival over the long term.

Risk of Recurrent CeAD After Pregnancy