Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT06503510

Role of Interleukin-13 Pathways on Pain and Itch Sensitivity

Led by Aalborg University · Updated on 2025-06-04

20

Participants Needed

3

Research Sites

103 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Atopic dermatitis (AD) is as chronic, inflammatory skin disorder affecting 20% of the world's population. Intense itch and skin pain are the main symptoms. Research has shown that the proteins interleukins are involved in inflammation and itch in atopic dermatitis. The medicinal product called Lebrikizumab, used for treatment of AD, has shown to block the interleukin called IL-13. The purpose of this experiment is to evaluate the role of IL-13 in itch in both healthy subjects and people with atopic dermatitis.

CONDITIONS

Official Title

Role of Interleukin-13 Pathways on Pain and Itch Sensitivity

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy men and women
  • Between 18 and 60 years of age
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Use of cannabis, opioids, or other drugs indicating drug addiction
  • History or current diagnosis of neurological, skin (including atopic dermatitis and psoriasis), immune, muscle, heart, or psychiatric disorders that may affect results
  • Presence of moles, wounds, scars, or tattoos in the treatment or test area
  • Current use of medications such as antihistamines, painkillers, systemic or topical corticosteroids
  • Consumption of alcohol or painkillers within 24 hours before or during study days
  • Acute or chronic pain
  • Participation in other clinical trials within one week prior to study entry (four weeks for pharmaceutical trials)
  • Inability to cooperate with study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Aalborg University

Gistrup, Aalborg, Denmark, 9260

Actively Recruiting

2

CNAP

Gistrup, Aalborg, Denmark, 9260

Active, Not Recruiting

3

Aalborg University

Aalborg, Denmark, Denmark, 9260

Not Yet Recruiting

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Research Team

S

Silvia Lo Vecchio

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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