Role of a Novel Implantable Loop Recorder in the Management of Premature Ventricular Contractions

What this Trial Is About

This observational study focuses on patients with Premature Ventricular Contractions (PVCs), either with symptoms or without, to better understand the occurrence of all types of cardiac arrhythmias detected through long-term monitoring. Researchers aim to assess the role of implantable loop recorders (ILRs) in managing PVCs and to investigate clinical, biomarker, and radiological signs of myocarditis in this group. The study is conducted at a single center and will follow about 50 patients over 12 months. Participants will be monitored using implantable loop recorders from the time they first present with PVCs or ventricular arrhythmias. These devices will continuously record heart rhythms to detect arrhythmias. Alongside this, patients will be evaluated for evidence of myocarditis through clinical assessments and biomarker and imaging tests. The study does not involve experimental treatments but focuses on monitoring and data collection. During the 12-month follow-up, patients will undergo evaluations to identify unrecognized myocarditis, monitor PVC burden, assess improvements in heart function such as left ventricular ejection fraction, and detect associated atrial and ventricular arrhythmias. The study includes regular assessments and data collection to understand the link between myocarditis and arrhythmias. Participants will be closely observed to gather information that may inform future management of PVCs using ILRs.

Role of Novel ILR in the Management of PVCs