Actively Recruiting
A Twenty-years' Experience in Pituitary Disease: Identification of Prognostic Factors in Pituitary Tumors
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-05-15
1600
Participants Needed
1
Research Sites
10 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying pituitary tumors, which are a varied group of tumors affecting the pituitary gland. This observational study focuses on collecting detailed clinical, biochemical, morphological, and pathological data from over 1600 patients who have undergone neurosurgical removal of pituitary tumors in the past 20 years. The goal is to develop a prognostic classification to better predict tumor behavior and outcomes, as current data on epidemiology and prognosis are inconclusive. The study involves patients who have had surgery for pituitary tumors, with data collected retrospectively and prospectively. The main focus is on monitoring the frequency of disease recurrence. Participants have been followed for at least two years after their tumor removal, allowing researchers to track tumor recurrence over time. Participants will be observed from enrollment through 24 months of follow-up to assess tumor recurrence. Researchers will gather information from medical records and follow-up visits to evaluate outcomes. This study does not involve any experimental treatment, but rather monitors surgical outcomes and tumor behavior to improve future understanding of pituitary tumors.
CONDITIONS
Brief Title
A Twenty-years' Experience in Pituitary Disease.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients underwent surgery for pituitary tumors
- Pathology diagnosis of pituitary tumors
- Patients older than 18 years at diagnosis of pituitary tumors
- At least 2 years of follow-up after diagnosis
You will not qualify if you...
- Age younger than 18 years
- Follow-up shorter than 2 years
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At least 2 years
Participants are observed for tumor recurrence and disease status after surgical resection of pituitary tumors.
Visits as per clinical follow-up schedule over 24 months
Trial Site Locations
Total: 1 location
1
Fondazione Policlinico Gemelli IRCCS
Rome, IT, Italy, 00168
Actively Recruiting
Research Team
F
Francesco Doglietto, Prof
S
Sabrina Chiloiro, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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