Actively Recruiting
Shear Wave Elastography for Carotid Atherosclerotic Plaques
Led by UPECLIN HC FM Botucatu Unesp · Updated on 2025-04-06
43
Participants Needed
1
Research Sites
148 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective diagnostic accuracy cohort study is to compare the accuracy of carotid atherosclerotic plaques stiffness assessed by shear wave elastography (SWE) with greyscale median values (GSM), magnetic resonance imaging (MRI) and histopathological findings in patients with carotid atherosclerotic plaques causing stenosis above 50%, symptomatic or not. The main question it aims to answer is: is the plaque stiffness correlatable with GSM values, MRI findings or histopathological findings? Participants will be subjected to a vascular ultrasound study in which the SWE and GSM will be assessed. The second imaging modality for stenosis confirmation will be MRI and patients with confirmed symptomatic stenosis above 50% or assymptomatic stenosis above 70% will be considered for surgery intervention (endarterectomy or angioplasty). Patients that undergo endarterectomy will have the carotid plaques subjected to a histopathological study. The study will not arbitrate about the treatment decision.
CONDITIONS
Official Title
Shear Wave Elastography for Carotid Atherosclerotic Plaques
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with atherosclerotic carotid plaques that develop stenosis superior to 50%.
You will not qualify if you...
- Previous cervical surgery;
- Previous cervical radiotherapy;
- Stenosis caused by vascular inflammatory diseases;
- Pregnant women;
- High carotid bifurcation (inaccessible by vascular ultrasound linear probe);
- Posterior acoustic shadowing that impair morphological evaluation of the plaque.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Sao Paulo State University
Botucatu, São Paulo, Brazil, 18618-970
Actively Recruiting
Research Team
P
Pedro L Mellucci Filho, M.D.
CONTACT
M
Marcone L Sobreira, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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