Actively Recruiting
Renal Cortical Stiffness Measured by Shear Wave Elastography for Evaluation of Hydronephrosis in Pregnancy: A Prospective Study
Led by Beni-Suef University · Updated on 2026-04-27
250
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hydronephrosis during pregnancy is often a normal condition but can sometimes indicate a blockage that needs treatment. Differentiating between normal and obstructive hydronephrosis is difficult using standard ultrasound methods. This study is a prospective observational investigation aiming to assess how well renal cortical stiffness measured by shear wave elastography (SWE) can distinguish between these two types in pregnant women. Pregnant women of at least 12 weeks gestation experiencing loin pain and showing hydronephrosis on ultrasound will be evaluated. The study involves clinical exams, lab tests, and ultrasound including SWE to measure kidney stiffness. SWE measurements will be taken in a specific position with multiple readings per kidney, and follow-up assessments will occur at 2-4 weeks, after any interventions, and 6-8 weeks after childbirth. Participants will undergo repeated evaluations including clinical, laboratory, and ultrasound measures. Researchers will analyze SWE's diagnostic accuracy using statistical methods and compare it with hydronephrosis grading and kidney cortex thickness. The primary focus is on how well SWE differentiates obstructive from physiological hydronephrosis at initial presentation, with ongoing monitoring to confirm results and guide management.
CONDITIONS
Brief Title
Shear Wave Elastography for Evaluation of Hydronephrosis in Pregnancy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant women at least 12 weeks gestation with loin pain
- Sonographic evidence of hydronephrosis
- Age 18 years or older
- Provided informed consent
You will not qualify if you...
- Chronic kidney disease
- Congenital renal anomalies
- Pre-eclampsia
- Poor acoustic window
- Contraindication to examination position
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Baseline at presentation
Participants undergo clinical evaluation, laboratory investigations, conventional ultrasound, and shear wave elastography (SWE) to assess renal cortical stiffness and hydronephrosis.
1 visit (in-person)
Duration - Up to 8 weeks postpartum
Participants are monitored with follow-up assessments including SWE and ultrasound after 2 to 4 weeks and again 6 to 8 weeks postpartum to evaluate the clinical course and resolution of hydronephrosis.
2 follow-up visits (in-person)
Trial Site Locations
Total: 1 location
1
Beni Suef university hospital
Banī Suwayf, Beni Suef Governorate, Egypt, 62511
Actively Recruiting
Research Team
M
Mahmoud Abdallah Mahmoud, lecturer of urology
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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