Actively Recruiting
Smartphone Based Digital Screening for Aortic Valve Stenosis
Led by Medical University Innsbruck · Updated on 2026-05-28
500
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Heart valve diseases are serious cardiovascular conditions common in older adults, with aortic valve stenosis being a frequent form. This condition narrows the valve between the heart and main artery, making the heart work harder over time. Symptoms often appear late, including shortness of breath and chest pain, making early detection challenging. The study explores a new approach using smartphones to screen for aortic valve stenosis, aiming to find a simple, affordable, and accessible alternative to echocardiography. The research involves using smartphones to record heart sounds and chest vibrations through built-in sensors like microphones and accelerometers. These recordings will be processed using artificial intelligence to identify signs of aortic valve stenosis. Several hundred patients with and without valve disease will participate, and smartphone results will be compared to standard echocardiography to evaluate accuracy and reliability. Participants will undergo a baseline visit where smartphone and echocardiographic assessments are performed. Researchers will measure the sensitivity and specificity of the smartphone-based algorithm, quality of the cardiac signals, and agreement with echocardiographic grading. Participants will be monitored for up to 12 months for major cardiac and cerebrovascular events. The goal is to develop a digital heart check that can be done easily at home using a smartphone.
CONDITIONS
Brief Title
Smartphone Based Digital Screening for Aortic Valve Stenosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- For group I: Moderate to severe aortic valve stenosis defined as AVA 4 1.5 cm by echocardiography
- For group II: No significant valvular heart disease
- No valvular prosthesis, pacemaker, or congenital heart defect
- Echocardiography performed within the last 90 days
- Provided written informed consent
You will not qualify if you...
- Did not sign the informed consent form
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo smartphone-based signal acquisition and echocardiographic assessments to detect moderate-to-severe aortic stenosis using a smartphone-derived algorithm.
1 baseline visit (in-person)
Duration - Up to 12 months
Participants are monitored for major adverse cardiac and cerebrovascular events (MACCE) for up to 12 months after the baseline visit.
Follow-up visits as needed for up to 12 months
Trial Site Locations
Total: 1 location
1
Department of Internal Medicine III
Innsbruck, Austria, 6020
Actively Recruiting
Research Team
M
Michael Schreinlechner, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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