Actively Recruiting
Solutions to the Challenges of Conduction System Pacing
Led by Imperial College London · Updated on 2025-07-14
300
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Conduction system pacing is a new way of stimulating the heart using pacemaker wires. Traditional pacemakers stimulate the heart muscle which causes disordered heart beats: the walls of the heart move at different times. This wears down the heart over time. Conduction system pacemakers stimulate the heart's electrical system directly producing natural heart beats that are much less disordered. Unfortunately, these pacemakers can only be implanted by a small group of experts at specialised centres with specialist equipment. This study aims to allow conduction system pacemakers to be offered to any patient at any hospital by simplifying the process of inserting the pacemaker wires and the improving the pacemaker's ability to interpret electrical traces. Firstly, the best locations in the heart for conduction system pacemaker wires using specialised electrical traces, MRI and ultrasound scans will be identified. Features that can be seen on X-ray to guide doctors to these locations will then be identified. Secondly, the investigators will collect electrical information from the pacemaker wires and additional electrical traces to develop an algorithm that can make the interpretation the electrical traces more accurate.
CONDITIONS
Official Title
Solutions to the Challenges of Conduction System Pacing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a ventricular pacing indication such as high grade atrioventricular block, symptomatic trifascicular or bifascicular block, or left bundle branch block for cardiac resynchronisation therapy
- Adults aged 18 to 100 years
- Able and willing to give consent
You will not qualify if you...
- Unable to give consent
- Children under 18 years and adults over 100 years
- Pregnant patients (female patients of child-bearing age will have a urine pregnancy test before the procedure as standard care)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Imperial College Healthcare Trust; Hammersmith Hospital
London, United Kingdom, W12 0HS
Actively Recruiting
Research Team
A
Akriti Naraen, MBChB
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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