Actively Recruiting

All Genders
NCT04772963

Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV)

Led by Fondation Ophtalmologique Adolphe de Rothschild · Updated on 2026-01-22

300

Participants Needed

1

Research Sites

262 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cerebral and medullary arteriovenous malformations (AVMs) lead to arterial and venous networks to communicate pathologically, creating an arteriovenous shunt. The occurrence of intracranial haemorrhage is the most important prognostic factor of AVMs because it is associated with a significant morbidity and mortality. The genetic, molecular and cellular mechanisms that cause vascular malformations of the central nervous system are partially known and the influence of genetic damage on the prognosis of AVMs is poorly known.

CONDITIONS

Official Title

Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient with a vascular malformation of the cerebral or medullary identified on diagnostic imaging (angio-CT, angio-MRI or diagnostic angiography) for which clinical monitoring alone or intervention (endovascular treatment, surgery or radiosurgery) is planned in the centres participating in the research.
Not Eligible

You will not qualify if you...

  • Pregnant, parturient or breastfeeding woman

AI-Screening

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Trial Site Locations

Total: 1 location

1

HOPITAL FONDATION Adolphe de ROTHSCHILD

Paris, France, 75019

Actively Recruiting

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Research Team

S

Stanislas Smajda, MD

CONTACT

A

Amélie Yavchitz, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Genetics of Central Nervous System Arteriovenous Malformations (GENE-MAV) | DecenTrialz