Pilot Study Comparing PluroGel to Standard Topical Dressing for Treating Partial Thickness Burn Injuries in Adults

What this Trial Is About

Burn injuries can cause long-lasting physical and mental challenges due to scarring and painful dressings. The usual treatment involves antibiotic topical dressings while waiting to determine the burn depth, followed by surgery for deeper burns. Assessing burn depth is complex and can take weeks, with surgical removal of tissue often removing some healthy tissue. New methods like hydro-dissection devices and enzymatic debridement have been explored but lack definitive proof of benefit and may sometimes cause harm. This trial is studying PluroGel, a gel that helps clean burn wounds by loosening and removing dead tissue while keeping the wound moist. Participants will receive either the standard antibiotic ointment and gauze dressing or PluroGel plus the standard dressing with moist gauze. Dressings are applied every Monday, Wednesday, and Friday, with moist gauze kept wet twice daily in the PluroGel group. This is a randomized, double-blind study comparing these two approaches. Participants will be monitored to see how much of the burn heals within 14 days and whether surgery is needed during this time. The study includes regular dressing changes and wound evaluations. The trial aims to gather evidence on the healing effects of PluroGel compared to standard care over this two-week period. Participation lasts at least 14 days, with close follow-up to assess wound healing and treatment safety.

A Study of Plurogel® Compared to Standard Topical Dressing in Burn Injuries