Study of Factors Affecting Outcomes After Paclitaxel Drug-Coated Balloon Angioplasty in Adults with Coronary Artery Disease

What this Trial Is About

Researchers are analyzing factors that affect outcomes after paclitaxel drug-coated balloon angioplasty in patients with de novo large-vessel coronary artery disease. This retrospective study reviews data from over 5000 patients to understand differences in baseline characteristics, lesion features, imaging results, hemodynamic parameters, and procedural approaches. The main focus is on cardiovascular events and angiographic outcomes at one year following treatment. The study involves reviewing records of patients who underwent paclitaxel drug-coated balloon angioplasty. It evaluates clinical events such as cardiovascular death and other cardiovascular complications within 12 months. Imaging outcomes like late lumen loss and restenosis rates are also assessed, including intracavitary imaging techniques such as OCT and IVUS. The study is observational and does not involve new treatments or interventions. Participants will have their medical and imaging data reviewed retrospectively. Researchers will measure major adverse cardiovascular events at 12 months and assess changes in the treated vessels using coronary angiography. The study includes patients aged 18 and older with confirmed large vessel coronary artery disease. Safety and clinical outcomes will be monitored through the review of existing clinical information and imaging records. The study is expected to be completed by the end of 2026.

A Retrospective Study on the Factors of Drug-coated Balloon Restenosis