The role of regional anaesthesia and multimodal analgesia in the prevention of chronic postoperative pain: a narrative review.
Y-Y K Chen, K A Boden, K L Schreiber
https://pubmed.ncbi.nlm.nih.gov/33426669Actively Recruiting
Led by Brigham and Women's Hospital · Updated on 2026-05-22
1000
Participants Needed
1
Research Sites
52 weeks
Total Duration
Researchers are investigating how regional anesthesia, which involves numbing medications like epidurals or nerve blocks, affects pain in patients undergoing various types of surgery, including thoracic, open abdominal, orthopedic, and spine surgeries. They aim to understand how different psychological factors such as anxiety, sleep issues, and concerns about pain influence the effectiveness of regional anesthesia. The study also explores how these factors impact opioid use after surgery and the development of chronic postsurgical pain. Participants in this observational study include patients who have surgery and may receive regional anesthesia or not. Some patients may also have an acute pain consultation before, during, or after surgery. The study does not assign treatments but observes patients based on whether they receive these procedures. The research uses surveys and interviews to capture patients' psychological profiles and their experiences with pain and anesthesia. During the study, participants will provide information through psychosocial surveys and recorded interviews. Researchers will collect data on pain scores over the first 24 hours after surgery, daily pain levels for a week, and opioid use during this time. The primary measurement is the highest pain score within the first 24 hours post-surgery. The study is designed to better understand how patient characteristics relate to pain management and opioid use after surgery.
CONDITIONS
Understanding the Acute Pain Phenotype in Patients Undergoing Surgery
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo thoracic, open abdominal, orthopedic, or spine surgery with or without regional anesthesia or acute pain consultation as part of their surgical care.
1 visit (in-person)
Duration - 7 days
Participants have daily assessments of pain scores and opioid consumption for up to 7 days after surgery.
Daily visits or assessments for up to 7 days
Total: 1 location
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Y
Yun-Yun K Chen, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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