Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT04715399

UPenn Observational Research Repository on Neurodegenerative Disease

Led by University of Pennsylvania · Updated on 2026-01-22

1000

Participants Needed

1

Research Sites

2609 weeks

Total Duration

On this page

Sponsors

U

University of Pennsylvania

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this study is to create a repository of both cross-sectional and longitudinal data, including cognitive, linguistic, imaging and biofluid biological specimens, for neurodegenerative disease research and treatment.

CONDITIONS

Official Title

UPenn Observational Research Repository on Neurodegenerative Disease

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • People diagnosed with neurodegenerative diseases such as frontotemporal degeneration, primary progressive aphasia, Lewy body disease, amyotrophic lateral sclerosis, progressive supranuclear palsy, corticobasal syndrome, posterior cortical atrophy, Alzheimer's disease, or Parkinson's disease
  • People with a family history of neurodegenerative disease, whether or not they have symptoms or carry mutations
  • People without any known neurological disease to provide control data
Not Eligible

You will not qualify if you...

  • Individuals under 18 years of age
  • People with conditions or situations that could confuse study results or interfere with participation, including neurological, psychological, cardiac, neurosurgical, or infectious conditions
  • Participants may be excluded from specific procedures for safety reasons, like those with non-MRI-safe metal implants or on blood thinners who cannot have lumbar punctures
  • Pregnant women; research activities that pose risk during pregnancy will be paused until after pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

E

Emily Xie

CONTACT

D

Dahlia Kamel

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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UPenn Observational Research Repository on Neurodegenerative Disease | DecenTrialz