Actively Recruiting
Imaging Studies in Corticobasal Syndrome
Led by Jennifer Whitwell · Updated on 2025-07-07
80
Participants Needed
1
Research Sites
300 weeks
Total Duration
On this page
Sponsors
J
Jennifer Whitwell
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary goal of this study is to investigate inflammation and white matter damage in corticobasal syndrome and determine whether these processes are related to each other. The investigator's will address our goal by using neuroimaging and blood plasma biomarkers, as well as molecular pathology.
CONDITIONS
Official Title
Imaging Studies in Corticobasal Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Meet possible or probable corticobasal syndrome criteria
You will not qualify if you...
- MRI contraindicated due to implanted device, severe claustrophobia, or similar reasons
- Concurrent illnesses or structural abnormalities that could explain CBS symptoms
- Mutation in the progranulin gene
- Previous treatment with anti-Ab2 therapy
- Pregnant women
- Currently taking daily anti-inflammatory medications such as NSAIDs or corticosteroids
- Generalized inflammatory conditions with recent treatment using immunosuppressive or anti-inflammatory drugs within 2 weeks of scanning
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
M
Megan J Meyer, M.B.A.
CONTACT
S
Sarah M Boland, CCRP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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