Comparing Photoplethysmographic Upstroke Time and Toe-Brachial Pressure Index for Detecting Peripheral Arterial Disease in Adults with Type 2 Diabetes

What this Trial Is About

Peripheral arterial disease PAD and type 2 diabetes are significant health concerns. In France, over one million people have PAD and more than 3.5 million have diabetes. Screening for PAD in diabetic patients is usually done with the Toe-Brachial pressure index TBi, which is time-consuming and technically challenging. This study evaluates a new photoplethysmographic PPG method to measure the upstroke time, which could provide a faster, easier, and less expensive way to assess peripheral blood flow in diabetic patients. The study will compare the upstroke time measured by the PPG method using the POPMETRE device with the traditional TBi method in adults with type 2 diabetes. This prospective study will take place in two centers, and each participant will have their upstroke time measured by the PPG device during a vascular medicine consultation for PAD screening or follow-up. The study aims to determine how well the PPG method matches the TBi measurements and its ability to detect significant PAD in diabetic patients. Participants will be adults with type 2 diabetes undergoing vascular assessments. Researchers will measure upstroke time with the device and compare it to TBi values. The main outcome is the comparison of these two measurement methods. Participants will be assessed during their routine consultations, and no masking or randomization is involved. The study will complete by December 2026, with ongoing data collection and analysis to understand the diagnostic value of the PPG technique.

Upstroke Time Measured by Photoplethysmography