Actively Recruiting

Age: 0Years - 18Years
All Genders
ID07099664

Use of the Aortic Time-velocity Integral Via Suprasternal Ultrasound to Search Preload Dependence in Paediatric Surgery Kid's Fluid Management (FM)

Led by University Hospital, Lille · Updated on 2026-05-22

90

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating whether measuring the variation in the aortic Time-velocity Integral (VTI) via suprasternal ultrasound can predict preload dependence in children undergoing surgery. This study focuses on pediatric patients under 18 years old who require general anesthesia for various procedures. The aim is to improve fluid management, as fluid overload after major surgery is linked to increased risks and complications, and current methods to predict preload dependence in pediatric anesthesia are limited. The study involves measuring the aortic VTI and cardiac output using a suprasternal Doppler probe after general anesthesia induction and fasting compensation. Patients' cardiac output changes are assessed after receiving a fluid volume of 10 ml/kg of crystalloid solution. The study examines whether differences in VTI variation correlate with patients who respond to volume expansion with a significant increase in cardiac output. Participants will undergo measurements of aortic VTI variation before surgery, after induction, and after fasting compensation, but before the surgical incision. Researchers will evaluate the proportion of patients suitable for suprasternal aortic measurements, determine optimal VTI variation thresholds for identifying preload dependence, and study correlations between fasting duration and preload dependence. The study is observational, with participant involvement focusing on ultrasound measurements and monitoring during anesthesia. Participation lasts through the perioperative period with no long-term follow-up specified.

CONDITIONS

Brief Title

Use of the Aortic Time-velocity Integral Via Suprasternal Ultrasound to Search Preload Dependence in Paediatric Surgery : Kid's Fluid Management (FM)

Who Can Participate

Age: 0Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient under 18 admitted to paediatric operating room for a surgical intervention, an endoscopy, an interventional radiology procedure or an imaging and needing a general anaesthesia.
Not Eligible

You will not qualify if you...

  • Condition preventing a suprasternal ultrasound (tracheostomy, spinal immobilization, suprasternal bandage)
  • Pathology disturbing respiratory variation of left ventricular stroke volume (pulmonary arterial hypertension, constrictive pericarditis, pericardial effusion, right ventricular dysfunction, complex congenital heart disease, aortic coarctation, patent ductus arteriosus)
  • Medical conditions where fasting compensation might be unsafe (anuric kidney failure, oedema, heart failure with reduced left ventricular ejection fraction, use of vasoactive drugs)
  • Opposition to participation in the study
  • Pregnant women
  • Patient with no security coverage
  • Inability to determine baseline cardiac output

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Preoperative period on the day of surgery

Participants undergo measurements of aortic Vmax and VTI with suprasternal doppler to assess cardiac output and preload dependence after general anaesthesia and fasting compensation.

1 visit during preoperative period

Trial Site Locations

Total: 1 location

1

chu de Lille

Lille, France

Actively Recruiting

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Research Team

M

Martin DUBERNET, Dr

J

Julien COROUGE, Dr

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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