What is the multivitamin/mineral supplement studying for perimenopause symptoms?

This trial is studying whether a 12-week daily multivitamin/mineral and herbal supplement can affect symptoms of perimenopause such as mood changes, sleep problems, and cognitive challenges. Researchers want to understand how such supplements may influence memory, concentration, sleep quality, and psychological well-being in women aged 40 to 60.

Who may be eligible for this perimenopause clinical trial?

Women aged 40 to 60 who are experiencing troublesome perimenopause symptoms but have not gone 12 months without menstruation may be eligible. Participants must consider themselves healthy and not be pregnant, lactating, or on certain medications affecting cognition or sleep. Please review eligibility criteria for more details.

Is there any cost to participate in this perimenopause clinical trial?

Study-related care, including the study supplements and all trial visits, is provided at no cost. However, personal travel expenses to attend visits may vary and are not guaranteed to be covered.

Actively Recruiting

Phase Not Applicable

Age: 40Years - 60Years

FEMALE

Healthy Volunteers

ID07242430

Effects of 12-week Multi-vitaminMineral Supplementation on Perimenopause Symptoms, Cognition, Sleep, and Psychological Well-being A Randomized Placebo-controlled Trial

Led by Northumbria University · Updated on 2026-05-29

Participants Needed

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Perimenopause is a transition phase before menopause, marked by symptoms such as mood changes, anxiety, sleep problems, hot flushes, night sweats, fatigue, and cognitive challenges. These symptoms can significantly impact womens quality of life. Although awareness of menopause has grown, research on nutritional approaches to manage these symptoms remains limited. This study aims to evaluate the impact of a 12-week multi-vitaminmineral and herbal supplement on perimenopause symptoms, memory, concentration, sleep, and psychological well-being compared to a placebo. Participants will be randomly assigned to one of two groups one taking a placebo capsule daily for 84 days, and the other taking a multi-vitaminmineral supplement daily for the same duration. The supplement includes herbal extracts and vitamins recommended by menopause societies. The study will compare the effects of these supplements on symptoms and cognitive function over the 12-week period. Throughout the study, participants will be assessed at the start, at 6 weeks, and at 12 weeks. Assessments include various memory and cognitive tests such as numeric and alphabetic working memory, 3-back task, word and picture recognition, as well as questionnaires on menopause quality of life, depression, anxiety, stress, mood, and sleep quality. The study monitors changes in these areas to understand the supplements effects on perimenopausal women aged 40 to 60 years.

CONDITIONS

Brief Title

12-week Multi-vitamin/Mineral Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being.

Who Can Participate

Age: 40Years - 60Years

FEMALE

Healthy Volunteers

Eligibility Criteria

You may qualify if you...

Self-assess as healthy
Report experiencing troublesome perimenopause symptoms in the past 6 months
Have not gone 12 months without menstruation (not post-menopausal)
Female aged 40 to 60 years

You will not qualify if you...

Post-menopausal (12 months with no periods)
Pregnant, lactating, or seeking to become pregnant
Nut allergy
Taken antidepressant, antianxiety, or other medications likely to affect cognition or sleep in past 6 months
Habitual multi-vitamin/mineral supplementation unless a 1-month washout period
Menopause symptoms medically induced
Receiving gender-affirming hormone therapy

Research Team

Crystal Haskell-Ramsay

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