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Study of Bone Regeneration Using 2D3D Imaging in Alveolar Ridge Preservation Surgery With Autologous Tooth Root Covers, Bone Grafts, and Vitamin D3 Treatment
Led by Chang Gung Memorial Hospital · Updated on 2024-12-02
48
Participants Needed
1
Research Sites
8 weeks
Total Duration
AI-Summary
What this Trial Is About
This research investigates alveolar ridge preservation after tooth extraction by examining different methods to support bone regeneration. It focuses on the use of autologous tooth root slices, bone graft materials, collagen plugs, and vitamin D3 to improve healing and bone formation in the extraction site. Advanced 2D and 3D imaging technologies are used to monitor bone regeneration without invasive biopsies. The study evaluates if combining these biological materials and treatments can increase bone formation rates and stabilize the wound more effectively than traditional methods. Participants are randomly assigned to one of four groups receiving different combinations of treatments bone graft with collagen plug alone bone graft, collagen plug, and local vitamin D3 bone graft, collagen plug, and autologous tooth root slices or bone graft, collagen plug, vitamin D3, and autologous tooth root slices. The autologous tooth root slices are placed over the extraction socket to seal it and help protect bone graft materials, while the skin flap is surgically raised to cover and stabilize the tooth root cover. This approach aims to reduce contamination and promote faster healing. Throughout the study, participants undergo imaging assessments including 3D computed tomography, periapical X-rays, and intraoral scans at the start and between weeks 12 to 16 after extraction. Implant stability is also measured between weeks 16 and 24. These evaluations help researchers observe bone regeneration progress and wound healing. The total participant involvement spans from initial tooth extraction through follow-up periods to assess treatment effects and implant stability.
CONDITIONS
Brief Title
2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone
Research Team
H
Hsiang Hsi Hong
W
Wen H Chi
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