Actively Recruiting
Efficacy of Manual Versus Rotary Degranulation Techniques on Clinical and Radiographic Outcomes of Alveolar Ridge Preservation: Randomized Clinical Trial
Led by Imam Abdulrahman Bin Faisal University · Updated on 2026-06-03
60
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating two common methods for cleaning tooth extraction sockets to see which leads to faster cleaning, less pain, and better bone healing. This study focuses on adults aged 18 to 65 who need teeth removed due to long-term root infections. The goal is to improve healing and prepare the jawbone for possible future dental implants by comparing manual curettage and rotary degranulation techniques. Participants will be randomly assigned to have their socket cleaned either manually using a surgical curette or with a small rotating diamond bur. After cleaning, all patients will receive a standardized bone graft and collagen membrane to help preserve the alveolar ridge. The procedure includes staining the socket with Toluidine Blue to check for remaining unhealthy tissue, with a single surgeon performing all treatments. Participants will be monitored during and after the procedure, with assessments including the time taken to clean the socket, the cleanliness confirmed by staining, bone changes measured by 3D X-rays at 3 and 6 months, and patient-reported pain and swelling during the first week. Researchers will also track any complications or healing issues. The study aims to enroll about 58 to 60 adults and lasts up to six months of follow-up.
CONDITIONS
Brief Title
Rotary Versus Manual Degranulation in Alveolar Ridge Preservation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients attending the College of Dentistry outpatient clinics
- Adults aged 18 to 65 years who need tooth extraction due to chronic root infection confirmed clinically and by X-ray
- Teeth confirmed by limited field-of-view cone-beam CT scan showing periapical pathology with intact socket walls
- Teeth suitable for atraumatic extraction without excessive bone removal
- Ability to provide informed consent, maintain good oral hygiene, and attend follow-up visits
You will not qualify if you...
- Acute infection at the tooth extraction site
- Thin buccal bone less than 1 mm on CT scan
- Severe periodontal disease with over 50% bone loss
- Grade III tooth mobility
- Root shapes that prevent instrument access
- Uncontrolled systemic diseases such as diabetes or immune disorders
- Pregnant or breastfeeding women
- Use of medications affecting bone such as long-term corticosteroids or bisphosphonates
- Allergy to penicillin or amoxicillin
- Poor oral hygiene, inability to care after surgery, or unwillingness to attend follow-ups
AI-Screening
AI-Powered Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day 0
Participants undergo tooth extraction followed by degranulation of the extraction socket using either rotary burs or manual curettage, then receive standardized alveolar ridge preservation with allograft and collagen membrane.
1 procedure visit (in-person)
Duration - Up to 6 months post-extraction
Participants are monitored for healing, pain, swelling, and complications with follow-up visits and assessments including cone-beam CT scans to evaluate socket volume and healing outcomes.
Follow-up visits at 1 week, 2 weeks, and at 3 and 6 months post-extraction
Trial Site Locations
Total: 1 location
1
College of Dentistry, Imam Abdulrahman Bin Faisal University
Dammam, Dammam, Saudi Arabia, 31441
Actively Recruiting
Research Team
Y
Yasser Mohammed Bin Khames, BDS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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