Actively Recruiting
Acute Ocular Effects of Cigarette Smoking
Led by Istanbul University · Updated on 2026-05-12
90
Participants Needed
1
Research Sites
10 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective study aims to evaluate the short-term effects of smoking on corneal tomographic and biometric measurements in healthy adults. After baseline examinations and measurements are taken in both smoking and non-smoking participants, the same measurements will be repeated after 10 minutes of external exposure, and within-group and between-group changes will be compared. The aim of the study is to determine whether acute smoking exposure leads to measurable immediate changes in corneal tomographic and biometric parameters.
CONDITIONS
Official Title
Acute Ocular Effects of Cigarette Smoking
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy adults aged 18 to 60 years
- Current smokers in the smoking group
- Never-smokers in the control group
- Willing and able to undergo ophthalmic examination and Pentacam AXL measurements
You will not qualify if you...
- History of ocular surgery or ocular trauma
- Presence of corneal disease, retinal disease, or ocular surface disorder
- Clinically significant dry eye disease
- Contact lens use within the last 2 weeks
- Use of medications that may affect the ocular surface or pupillary dynamics, including anticholinergics or sympathomimetics
- Systemic diseases such as diabetes mellitus or hypertension
- Former smoking history in the control group
- Use of electronic cigarettes or other tobacco products
- Inability to cooperate adequately for accurate measurement
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Istanbul University, Istanbul Faculty of Medicine
Istanbul, Turkey (Türkiye), 34093
Actively Recruiting
Research Team
S
Semih Çakmak
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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