Actively Recruiting

Phase Not Applicable
Age: 5Years - 18Years
All Genders
ID05383092

Adapted Physical Activity for Children Treated With Cancer and Insulin Sensitivity

Led by University Hospital, Toulouse · Updated on 2023-09-21

60

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying children aged 5 to 18 years who have solid cancer or blood-related cancers to understand how intense physical activities or stretching affect insulin sensitivity and other metabolic, motor, and nutritional factors. The study aims to observe whether intense physical activity improves these health measures compared to a stretching program. Children are included at the start of their cancer treatment, with a focus on their first treatment experience and a life expectancy exceeding six months. The study involves two different physical activity programs lasting six months: one intense adapted physical activity combining aerobics and muscle strengthening, and another stretching program. Children participate in sessions two to three times a week, either during hospital stays or via videoconference at home. The intense activity sessions last 30 minutes for younger children and 60 minutes for older children. Evaluations occur at the beginning, at three and six months during the program, and follow-ups are done six and eighteen months after the programs end. Participants will undergo metabolic, motor, and nutritional assessments at scheduled time points throughout the study and after completion. The research team will monitor insulin sensitivity as the main outcome. Children receive personalized physical activity sessions adapted to their abilities and preferences. The overall participation lasts up to about two years, including initial treatment and follow-up evaluations to track the long-term effects of the physical activity programs.

CONDITIONS

Brief Title

Adapted Physical Activity for Children Treated With Cancer and Insulin Sensitivity

Who Can Participate

Age: 5Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 5 and 18 years old
  • Diagnosed with solid cancer or hematological disease
  • Receiving first treatment in pediatric oncology and hematology department
  • Estimated life expectancy at diagnosis greater than 6 months
Not Eligible

You will not qualify if you...

  • Unable physically or psychologically to follow an adapted physical activity program
  • Pre-existing heart disease unsuitable for adapted physical activities
  • Known type 1 diabetes
  • Obesity defined by body mass index at or above the International Obesity Task Force 25 threshold

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 months

Participants engage in an adapted physical activity program combining aerobics and muscle strengthening tailored to their needs. Sessions occur 2 to 3 times a week during hospitalizations or by videoconference at home.

Physical activity sessions 2 to 3 times per week; Evaluations at month 1, 3, and 6

Follow-up

Duration - 18 months

Participants are evaluated to assess outcomes related to insulin sensitivity after completing the physical activity program.

Evaluations at 6 and 18 months after program completion

Trial Site Locations

Total: 1 location

1

PASQUET Marlène

Toulouse, France, 31

Actively Recruiting

Loading map...

Research Team

M

Marlène PASQUET, MD, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

Similar Trials

A Hypnosis-based Group Intervention to Improve Quality of Li...

Pediatric Cancer

Actively Recruiting

1 location

Phase I First in Human Study of CBA-1205, Anti-DLK1 Monoclon...

Solid Tumors

Actively Recruiting

5 locations

A Prospective Clinical Cohort Study on Stratified Treatment ...

Rhabdomyosarcoma

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Study protocol of an early randomized intervention trial assessing the metabolic effects of two levels of exercise intensity in children undergoing cancer treatment: the APACIS study.

Justine Thomas, Thomas Filleron, Françoise Auriol...

https://pubmed.ncbi.nlm.nih.gov/40346598