Study of Biomarkers for Diagnosing and Predicting Outcomes in Aortic Aneurysm and Dissection

What this Trial Is About

This research aims to evaluate biomarkers for the diagnosis and prognosis of aortic aneurysm and aortic dissection. It includes a discovery phase with age- and sex-matched case-control groups for various conditions including aortic dissection, acute myocardial infarction, pulmonary embolism, aortic aneurysm without dissection, and healthy controls. The study also follows patients with confirmed aortic aneurysm and dissection to assess outcomes like mortality. The study has two parts a retrospective diagnosis phase and a prospective prognosis phase. Patients are enrolled based on clinical suspicion or confirmed diagnosis. Biomarker levels are categorized into thirds for analysis. The primary focus is on all-cause mortality and in-hospital mortality as outcome measures collected from medical records and follow-up visits over an average of 6 months to 2-4 years. Participants undergo medical record reviews and follow-up visits to collect data on diagnosis and prognosis. Researchers monitor survival outcomes and biomarker levels over time. The study involves adults aged 18 to 80 years and tracks patient health status through medical documentation and follow-ups to better understand disease progression and outcomes.

Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) Study