Actively Recruiting

Age: 60Years +
All Genders
NCT06580158

AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction

Led by Mayo Clinic · Updated on 2026-03-04

2000

Participants Needed

1

Research Sites

120 weeks

Total Duration

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AI-Summary

What this Trial Is About

Two recently developed artificial intelligence-enabled electrocardiogram (AI-ECG) models have been developed to detect aortic stenosis (AS) and diastolic dysfunction (DD). AI-ECG for AS has a sensitivity of 78% and specificity of 74%, and AI-ECG for DD has a sensitivity of 83% and specificity of 80%. However, these models have never been prospectively applied to diagnose AS or DD, which may be useful for patients and providers from a diagnostic and prognostic perspective and especially in settings where access to higher- level medical care is limited. In this study, we aim to determine the clinical utility of these AI-ECG models by prospectively applying them to an outpatient cohort and then completing a focused point-of-care ultrasound to evaluate those who are AI-ECG positive for AS and DD.

CONDITIONS

Official Title

AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 60 years of age or older
  • Have a scheduled clinical electrocardiogram (ECG) performed
Not Eligible

You will not qualify if you...

  • Be younger than 60 years old
  • Not scheduled for a clinical electrocardiogram (ECG)
  • Unable to provide consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

B

Brian Rudquist

CONTACT

J

Jae Oh, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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