Observing Changes in Ascending Aortic Size After Transcatheter Aortic Valve Replacement in Patients with Severe Aortic Stenosis

What this Trial Is About

This research aims to evaluate how the ascending aortic diameter changes in patients who undergo transcatheter aortic valve replacement TAVR for aortic stenosis. It particularly focuses on whether the diameter increases or remains stable after the procedure, especially in those with preoperative aortic dilatation. The study also seeks to identify factors that influence postoperative aortic dilatation in these patients. All participants undergo transfemoral TAVR, a procedure where the aortic valve is replaced through an artery in the leg. This observational study includes patients with severe aortic stenosis who are at high risk for traditional surgical valve replacement and who are suitable for this vascular access. The study does not involve additional treatments but monitors patients over time after their TAVR procedure. Participants will be followed to assess changes in the ascending aortic diameter at one and two years after TAVR. Researchers will also track rates of mortality and adverse aortic events during this period. Data collection includes clinical evaluations and imaging to measure aortic changes and monitor patient health outcomes throughout the study duration, which is planned to continue until March 2025.

Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement