Actively Recruiting

All Genders
NCT05739253

Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement

Led by China National Center for Cardiovascular Diseases · Updated on 2025-02-10

480

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to assess the changes of ascending aortic diameter in patients undergoing transcatheter aortic valve replacement. The main questions it aims to answer are: 1. whether the ascending aortic diameter increases or remains stable after transcatheter aortic valve replacement, especially in patients with preoperative ascending aortic dilatation; 2. the determinants of postoperative ascending aortic dilatation.

CONDITIONS

Official Title

Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Severe aortic stenosis defined as an aortic valve area of 1cm2 or less or an indexed aortic valve area of 0.6cm2/m2 or less
  • Presence of clinical symptoms defined as a New York Heart Association functional class of 2 or more
  • High risk of surgical aortic valve replacement
  • Suitability for a transfemoral vascular access
Not Eligible

You will not qualify if you...

  • Dominant aortic regurgitation
  • History of surgical or transcatheter aortic valve replacement
  • History of aortic surgery
  • Connective tissue disorders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Beijing, Beijing Municipality, China, 100037

Actively Recruiting

Loading map...

Research Team

X

Xiangbin Pan, Dr

CONTACT

K

Kang An, Dr

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement | DecenTrialz