Studying Motor Reserve and Movement Patterns in Adults with Mild Cognitive Impairment and Healthy Adults

What this Trial Is About

Mild Cognitive Impairment MCI is a condition linked to an increased risk of developing dementia. While cognitive changes have been the main focus, this research is exploring how motor changes may also appear early in cognitive decline and could serve as early signs of disease. The study aims to better understand motor reserve, which is how motor abilities might help compensate for cognitive decline, by examining both healthy people and those with MCI through detailed assessments. Participants will undergo a multidimensional evaluation including clinical and neuropsychological tests, standardized motor tasks, and precise movement analysis using a sensor glove device called the Hand Test System HTS. This device records objective motor data during tasks to characterize motor performance. The study includes two groups patients with MCI and healthy controls. No experimental treatments are given procedures are strictly for observation and research. Throughout the study, participants will complete assessments like finger tapping tests to measure motor skills alongside cognitive evaluations. Researchers will analyze how motor and cognitive reserves relate to clinical and neuropsychological status. The study plans to enroll about 200 participants aged 40 to 85 years and will help identify possible motor biomarkers for early cognitive decline. The study runs until July 2027 and involvement includes baseline motor and cognitive testing with no therapeutic interventions.

Assessment of Motor Reserve in the Preclinical Stages of Dementia