Actively Recruiting

Phase Not Applicable
Age: 60Years - 85Years
All Genders
Healthy Volunteers
ID06918704

Behavioral Intervention Development Core - Working Memory Digital Intervention in Aging

Led by University of California, San Francisco · Updated on 2026-04-01

150

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to evaluate whether engaging with digital interventions can improve cognitive functions, specifically working memory and inhibitory control, in older adults. The study focuses on medically healthy seniors, including those with mild cognitive impairment but without dementia, to understand if these digital tools may help enhance cognitive skills related to aging. Participants will be randomly assigned to one of two digital intervention groups to compare their effects. Participants will receive an iPad tablet and be randomly assigned to use either the Coherence app, which involves music-based rhythm training, or the Worder app, a word search game. They will be asked to train with their assigned app for 25 to 45 minutes per day, five days a week, over a period of up to eight weeks, totaling 1000 minutes of training. The study includes a baseline assessment, the intervention period, a post-intervention assessment, and a follow-up assessment six months later. Throughout the study, participants will complete web-based cognitive assessments and surveys at baseline, immediately after the intervention, and six months following the intervention. These assessments measure various cognitive abilities including working memory, inhibitory control, long-term memory, and sustained attention. Surveys will also gather information on stress levels, health background, and expectations. Participants can complete assessments across multiple sessions and will keep the iPad as a gift after finishing all study activities.

CONDITIONS

Brief Title

BID WM Digital Intervention in Aging

Who Can Participate

Age: 60Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Minimum of 12 years of education
  • Fluency in English
  • Normal or corrected-to-normal vision
  • Medically healthy older adults including those with below-average cognitive performance or mild cognitive impairment without dementia
  • Age between 60 and 85 years
Not Eligible

You will not qualify if you...

  • Under the age of 60
  • Clinical diagnosis of neurological or psychiatric disorder
  • Visually or hearing impaired without correction to normal
  • Clinical diagnosis of dementia or AD8 score greater than 3
  • Regularly practicing a musical instrument one or more times per week within the last year
  • Having 10 or more years of formal musical instrument training

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Baseline Assessment

Duration - Up to 1 day, can be completed across more than one session

Participants complete web-based cognitive assessments and surveys addressing various cognitive functions and background health information.

1 to 2 visits (web-based)

Intervention

Duration - Up to 8 weeks

Participants engage with the assigned intervention app on an iPad for 25-45 minutes per day, 5 days a week, for up to 8 weeks, totaling 1000 minutes of training.

Daily sessions, 5 days per week

Post Intervention Assessment

Duration - 1 day

Participants complete the same cognitive assessments and surveys as at baseline to measure outcomes immediately after the intervention.

1 visit (web-based)

Follow-Up Assessment

Duration - 1 day

Participants complete the same cognitive assessments and surveys 6 months after the intervention to assess long-term outcomes.

1 visit (web-based)

Trial Site Locations

Total: 1 location

1

University of California, San Francisco

San Francisco, California, United States, 94621

Actively Recruiting

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Research Team

M

Melissa Arioli

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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