Australian Barrett's Cohort With Dysplasia and Early Cancer Study

What this Trial Is About

Researchers are collecting observational data to understand the management and outcomes for patients with Barrett's oesophagus who have high grade dysplasia or early intramucosal carcinoma. This study also follows patients with low grade dysplastic and non-dysplastic Barrett's oesophagus to observe the natural progression of the condition over time. The focus is on gathering real-world information about these patients to improve knowledge about their disease course and treatment effects. This is an observational study without experimental treatments. It includes patients diagnosed with Barrett's oesophagus who have either high grade dysplasia or early cancer changes in the oesophagus. Participants are monitored during their usual care and Barrett's excision procedures, with no assigned interventions or randomization. The study observes outcomes and any adverse events that occur during and up to five years after these procedures. Participants undergo regular monitoring to track any serious or non-serious adverse events related to their Barrett's oesophagus treatment. Data collection includes clinical assessments and follow-up visits as part of routine care. The primary outcome measured is the number of adverse events during Barrett's excision, with secondary outcomes capturing adverse events up to five years post-procedure. This long-term observation helps researchers understand the safety and natural history of Barrett's oesophagus management over a decade-long timeframe.

Australian Barrett's Cohort With Dysplasia and Early Cancer Study