Evaluation of Barretts Esophagus Using the NaviCam Detachable String Capsule for Screening and Surveillance in Adults

What this Trial Is About

Researchers are evaluating a non-invasive method using the NaviCam Detachable String Capsule to improve viewing of the esophagus for detecting Barretts Esophagus. This study involves adults aged 22 and older, including those diagnosed with Long Segment Barretts Esophagus, Short Segment Barretts Esophagus, and patients with Gastro Esophageal Reflux Disease GERD eligible for Barretts screening. The goal is to enhance detection accuracy by assessing the esophageal lining. Participants will swallow the NaviCam capsule with water while sitting upright. The capsule will travel to the stomachs entry point, then be slowly pulled back using a string to inspect different sections of the esophagus under real-time video guidance. Images will be captured at two frames per second to help identify abnormal tissue. The study includes different groups based on Barretts Esophagus type or GERD diagnosis. Throughout the procedure, researchers will monitor the detection of columnar lined epithelium in the esophagus within 30 minutes. Participants will also complete assessments measuring anxiety and discomfort shortly after the procedure and up to seven days later. The study will last from the initial procedure through follow-up assessments, ensuring safety and gathering detailed information about the capsules effectiveness for esophageal evaluation.

Navicam for Detection of Barrett's Esophagus