Actively Recruiting

Phase Not Applicable
Age: 50Years - 99Years
All Genders
Healthy Volunteers
ID06544876

Balance Control and Recovery in Diabetes Peripheral Neuropathy

Led by Lisa Griffin · Updated on 2024-08-09

60

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the effects of diabetic peripheral neuropathy (DPN) on balance control, balance recovery, and muscle electrical activity in adults aged 50 and older. This condition affects peripheral nerves and muscle strength, increasing fall risk and feelings of instability. The study aims to compare muscle activity and balance during movements like sitting to standing and to assess responses to balance disturbances while standing. Participants will undergo tests including sit-to-stand and stand-to-sit movements, as well as standing on a treadmill that moves slightly side to side to measure balance recovery. Surface sensors will record muscle activity, and MRI scans will measure nerve diameter. Muscle strength in the legs will also be assessed. The study includes groups of healthy younger adults, healthy older adults, and older adults with diabetic peripheral neuropathy. During the study, participants will have body measurements taken and sensations tested in the feet. Researchers will monitor balance and muscle responses using force plates, cameras, and electromyography immediately after interventions. Outcome measures include center of pressure, center of mass, joint moments, muscle activity, and local dynamic stability. The total participation period is not specified but includes assessments conducted during the first session immediately after the interventions.

CONDITIONS

Brief Title

Balance Control and Recovery in Diabetes Peripheral Neuropathy

Who Can Participate

Age: 50Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 50 to 99 years
  • Diagnosed with type II diabetes with peripheral neuropathy
Not Eligible

You will not qualify if you...

  • Presence of foot ulcers
  • Partial amputation
  • History of stroke
  • Painful neuropathy
  • Inability to stand or walk independently

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 1 day

Participants perform balance and muscle activity tests including sit-to-stand, stand-to-sit, and standing perturbation tasks to assess balance control and recovery.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

The University of Texas at Austin

Austin, Texas, United States, 78712

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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