Digital Behavioral Interventions Using Memory and Word Puzzle Games to Improve Long-Term Memory and Cognitive Function in Older Adults with Mild Cognitive Impairment

What this Trial Is About

Researchers are investigating whether two different digital games can help improve long-term memory and cognitive control in older adults, including those with mild cognitive impairment MCI. The study aims to compare the effects of a navigation game and a word puzzle game on memory performance. This research is conducted as a randomized controlled trial using a web-based platform called Neuroscape Nexus. Participants receive an Apple iPad preloaded with one of two study apps a navigation game designed to provide an immersive spatial learning experience, or a word puzzle game similar to Boggle. They are asked to complete 45 minutes of training several days a week over 8 weeks, totaling 1000 minutes. The study includes a baseline assessment, an immediate post-training assessment, and a follow-up assessment six months after training ends. All study activities are done remotely from participants homes. Assessments include surveys and brief tests of memory and attention, each lasting up to 120 minutes and possibly completed over multiple sessions. Researchers will measure changes in recognition memory and cued recall memory immediately after training and at six months follow-up, as well as changes in working memory. Participants receive reminders and track their progress through the study platform throughout their involvement.

BID LTM Digital Intervention in Aging