Actively Recruiting

Phase Not Applicable
Age: 60Years - 85Years
All Genders
NCT06916221

BID LTM Digital Intervention in Aging

Led by University of California, San Francisco · Updated on 2026-04-02

150

Participants Needed

1

Research Sites

153 weeks

Total Duration

On this page

Sponsors

U

University of California, San Francisco

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Healthy aging is typically accompanied by diminished capability for learning and retrieval of high-fidelity long-term memory (LTM). The decline in these faculties is accelerated and becomes significant deficits in LTM and cognitive control functions at the level or a diagnosis of Mild Cognitive Impairment (MCI). Training with the navigation game, relative to training with control games, is expected to improve LTM performance for older adult participants. Researchers will compare two different digital interventions to assess whether they may be helpful in improving cognitive function. Participants will conduct study activities remotely (e.g., at-home): 1. Baseline Assessment. Complete a series of cognitive assessments and surveys. 2. Intervention. Engage in a digital intervention for up to 8 weeks. 3. Post Intervention Assessment. Complete the same cognitive assessments and surveys as the Baseline Assessment. 4. Follow-Up Assessment. Six months after the intervention ends, participants will complete the same cognitive assessments and surveys as the Baseline Assessment.

CONDITIONS

Official Title

BID LTM Digital Intervention in Aging

Who Can Participate

Age: 60Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Minimum of 12 years of education
  • Fluent in English
  • Normal or corrected-to-normal vision
  • Normal or corrected-to-normal hearing
  • Medically healthy older adults, including those with mild cognitive impairment (MCI) without dementia
Not Eligible

You will not qualify if you...

  • Under 60 years of age
  • Clinical diagnosis of neurological or psychiatric disorder
  • Clinical diagnosis of dementia or AD8 score greater than 4
  • Uncorrected visual or hearing impairments
  • Regularly practicing a musical instrument one or more times per week within the last year
  • 10 or more years of formal musical instrument training

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California, San Francsico

San Francisco, California, United States, 94158

Actively Recruiting

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Research Team

M

Melissa Arioli, AB

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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