Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT04934007

Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder

Led by Centre Hospitalier Henri Laborit · Updated on 2026-01-13

136

Participants Needed

2

Research Sites

312 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

According to the literature the lateral part of the Orbito Frontal Cortex (lOFC) is a relevant bilateral target for repetitive Trans-cranial Magnetic Stimulation (rTMS) in Obsessive Compulsive Disorder (OCD). Both hemispheres are concerned in terms of target.

CONDITIONS

Official Title

Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged 18 to 65 years, male or female
  • Diagnosis of Obsessive-Compulsive Disorder
  • Failed to respond to at least two different pharmacological treatments used for at least 6 weeks
  • Affiliation to a social security system (recipient or assignee)
  • Signed written informed consent form
Not Eligible

You will not qualify if you...

  • Diagnosis of another psychiatric disorder (except for anxious disorders)
  • Diagnosis of significant active medical illness
  • Pregnancy or nursing
  • Neurological illness
  • History of seizures
  • Presence of pacemakers, mobile metal implants, implanted medical pumps, or metal clips inside the skull
  • Change in medication during the trial; treatment must be stable for at least 3 weeks before day 0
  • Female subjects of child-bearing age not using reliable contraception
  • Patient under curators
  • Patient hospitalized under duress
  • Patient unable to give informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Sorbonne University, Pitié-Salpêtrière Hospital

Paris, France

Actively Recruiting

2

Centre Hospitalier Henri Laborit

Poitiers, France, 86021

Actively Recruiting

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Research Team

G

Ghina Harika-Germaneau, MD, PhD

CONTACT

N

Nematollah Jaafari, PR

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder | DecenTrialz