Actively Recruiting
Pilot Study to Evaluate Substances in Sweat, Saliva, and Blood for Patients with Chronic or Infectious Diseases
Led by City of Hope Medical Center · Updated on 2025-11-10
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
C
City of Hope Medical Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating new home-based methods to measure medication and chemical concentrations in sweat and saliva compared to standard blood tests in patients with chronic or infectious diseases who are receiving medications. The study aims to see if a smart wristband can accurately monitor substances like electrolytes and metabolites in sweat, which may help in health monitoring and disease diagnosis. This pilot observational study is focused on assessing the feasibility of these wearable sweat sensors. Participants provide sweat samples using a Macroduct Sweat Collection System, saliva samples, and blood samples within 24 hours after taking their medications. They also complete short questionnaires lasting 5 to 10 minutes and allow their medical records to be reviewed. The study collects samples and data to compare the new home-based methods against the standard liquid chromatography-mass spectrometry of plasma. During the study, patients are followed periodically after completing sample collection to monitor results and assess feasibility. Researchers measure how well the home-based sampling predicts medication levels and observe plasma concentrations within 4 hours. The study includes ongoing follow-up to evaluate the ease of obtaining home-based samples and to review medical data over time.
CONDITIONS
Brief Title
Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled to receive medications including cyclophosphamide, mycophenolic acid, mycophenolate mofetil, metformin, or busulfan as part of treatment
- Diagnosis of chronic or infectious disease
- Willing to provide blood, sweat, and saliva samples
- Agree to medical record review
You will not qualify if you...
- Allergy to pilocarpine
- Difficulty understanding written English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Within 24 hours after medication administration
Participants provide sweat, saliva, and blood samples within 24 hours after taking their medication. They also complete a short questionnaire and have their medical charts reviewed.
1 visit (in-person) for sample collection and questionnaire completion
Duration - Up to 4 hours post-sampling and periodic follow-up thereafter
Participants are followed up periodically after completing the sample collection phase.
Periodic follow-up visits
Trial Site Locations
Total: 1 location
1
City of Hope Medical Center
Duarte, California, United States, 91010
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here