Prospective Study on Treatments and Outcomes in Carbon Monoxide Poisoning Patients in Korea

What this Trial Is About

Researchers are studying patients who have experienced carbon monoxide CO poisoning to understand how different treatments affect their recovery. This observational study aims to evaluate the effects of therapies such as hyperbaric oxygen therapy HBO, therapeutic hypothermia TH, and other drugs on short- and long-term outcomes. The study also investigates brain and heart complications caused by CO poisoning and how these complications relate to patient prognosis. Participants diagnosed with acute CO poisoning will undergo various assessments, including cardiac MRI, cardiac CT, transthoracic echocardiography TTE, brain MRI, neurocognitive function tests, and laboratory tests. Treatments such as HBO and TH are used as part of medical care and monitored throughout the study. The study focuses on tracking responses to these treatments and the development of neurocognitive and psychological effects over time. During the study, subjects are regularly monitored by physicians. Evaluations occur at several time points including 1 month, 6 months, 12 months, and up to 5 years after CO exposure. Researchers measure therapeutic responses, brain and heart injuries, neurocognitive function, psychological outcomes, and mortality. The study collects detailed imaging and laboratory data to understand complications and their impact on recovery, with ongoing follow-up to capture both immediate and long-term effects.

CARbon monoxidE intoxiCatiOn in Korea: Prospective Cohort (CARE CO Cohort)