Study of Cardiopulmonary Exercise Testing and Oscillometry to Evaluate Shortness of Breath in Adults

What this Trial Is About

Researchers are investigating if airway resistance and pressure, measured by a device called Oscillometer, relate to abnormal results on Cardiopulmonary Exercise Testing in people experiencing unexplained shortness of breath. This observational study aims to better understand the link between breathing difficulties and exercise testing findings in adults. The study is led by the University of Rochester. Participants will undergo Cardiopulmonary Exercise Testing and have their respiratory system impedance measured by the tremoFlo C-100 Airwave Oscillometry System, which uses the Forced Oscillation Technique. This device measures how airflow and pressure behave during breathing. The study focuses on individuals referred specifically for exercise testing due to unexplained dyspnea. During the study, participants will perform breathing tests and exercise testing while researchers collect data on respiratory resistance and reactance. The main outcome measured is the average respiratory system resistance and reactance recorded approximately on the first day. Participants must be able to understand English and willing to perform the breathing tests. The study began in October 2024 and is expected to continue until November 2026.

Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea