Intracerebral Hemorrhage in Autosomal Dominant Cerebral Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.
Fangwei Hu, Weijie Xie, Mengting Fan...
https://pubmed.ncbi.nlm.nih.gov/40067051Actively Recruiting
Age: 18Years - 100Years
All Genders
ID04318119
Cerebral Small Vessel Disease Registry Study
Led by Bin Cai · Updated on 2023-09-28
3000
Participants Needed
1
Research Sites
313 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a prospective multicenter observational study to understand the clinical spectrum and natural progression of Cerebral Small Vessel Disease (CSVD). The study aims to assess clinical, genetic, and epigenetic features in patients with CSVD, identify independent imaging markers, and improve clinical management of this condition. This study is sponsored by Bin Cai and follows patients over many years to gather extensive data on this disease. Participants will be observed without receiving experimental treatments, with a focus on monitoring brain imaging features related to CSVD. These include MRI assessments for microbleeds, white matter hyperintensity, lacunes, perivascular spaces, and brain atrophy. The study will track the development and burden of these imaging markers over time to better understand disease progression. During the study, participants will undergo regular evaluations that include MRI scans and clinical assessments to document changes in their condition. Researchers will collect data from enrollment until death or up to 30 years, focusing on overall patient outcomes and imaging findings. The study does not involve any intervention but requires participants to cooperate with assessments and imaging procedures to contribute valuable information to the understanding of CSVD.
CONDITIONS
Brief Title
Cerebral Small Vessel Disease Registry Study
Who Can Participate
Age: 18Years - 100Years
All Genders
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Age over 18 years
- At least one MRI characteristic of Cerebral Small Vessel Disease: recent small subcortical infarct, lacune of presumed vascular origin, white matter hyperintensity of presumed vascular origin, perivascular space, cerebral microbleeds, or brain atrophy
You will not qualify if you...
- Unable to cooperate with inspectors
- Non-vascular white matter lesions
- Other cognitive diseases such as Alzheimer's disease, Parkinson's disease, or thyroid disease
- Serious systemic illness such as heart, liver, kidney disease, or major mental illness
- Contraindications for imaging examination
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Up to 30 years
Participants undergo MRI scans to assess characteristics related to cerebral small vessel disease.
Periodic MRI assessments over time
Long-term Monitoring
Duration - Up to 30 years
Participants are observed over time to monitor overall outcomes and changes in cerebral small vessel disease markers.
Regular follow-up visits for assessments
Trial Site Locations
Total: 1 location
1
Department of Neurology , First Affiliated Hospital Fujian Medical University
Fuzhou, Fujian, China, 350004
Actively Recruiting
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Research Team
B
Bin Cai, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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