Stroke: patient characteristics and quality of life of caregivers.
Tatiana Ferreira da Costa, Thayris Mariano Gomes, Lia Raquel de Carvalho Viana...
https://pubmed.ncbi.nlm.nih.gov/27783737Actively Recruiting
Age: 18Years +
All Genders
Healthy Volunteers
ID06443268
Cerebrovascular Disease: Quality of Life (CODE: QoL)
Led by University of Zurich · Updated on 2024-06-05
680
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the quality of life, stress levels, and caregiver burden in patients who have experienced a stroke and their caregivers. The study aims to identify factors affecting these aspects in both patients and their caregivers, comparing them to a group without stroke to establish a baseline. This observational study seeks to better understand how stroke impacts daily life and well-being in Switzerland, where stroke is a common cause of sudden life changes for patients and their relatives. Participants include stroke patients diagnosed with ischemic or hemorrhagic stroke, transient ischemic attack, or intracerebral hemorrhage, as well as their caregivers. A comparison group of individuals without recent stroke or disability is also included. Over a 12-month period, researchers will collect data at baseline, 3 months, and 12 months using questionnaires and biological samples such as hair for stress hormone analysis and blood tests. Both patients and caregivers will be assessed using various quality of life, stress, and neurological functioning measures. During the study, participants will complete questionnaires covering quality of life, anxiety, depression, caregiver burden, and other relevant factors. Biological markers including cortisol in hair, fasting glucose, lipid profiles, and thyroid hormone levels will be measured from blood samples. Clinical assessments such as neurological function and vital signs will also be performed. The main outcome is quality of life measured by the Short Form-36 questionnaire, tracked over time to understand changes after stroke events. The study will last up to 12 months with repeated assessments to monitor well-being and stress in stroke patient-caregiver pairs and controls.
CONDITIONS
Brief Title
Cerebrovascular Disease: Quality of Life (CODE: QoL)
Who Can Participate
Age: 18Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Participants must be over 18 years old
- Patients diagnosed with transient ischemic attack, ischemic stroke, or intracerebral hemorrhage and their caregivers
- Hospitalized or ambulatory patients included within 28 days from the stroke event
- Patients and caregivers must be able to provide informed consent
- Patients and caregivers must be willing to participate
- Control participants must have no previous stroke or stroke more than 3 years ago
- Control participants must have no significant disability (maximum Modified Rankin Scale 1)
- Control participants must be ambulatory patients at the University Hospital of Zurich
You will not qualify if you...
- Use of steroid hormone medications (such as prednisone, prednisolone, dexamethasone, methylprednisolone, hydrocortisone) within the last 3 months
AI-Screening
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Complete this quick 3-step screening to check your eligibility
1
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Your Study Journey
Screening
Duration - Up to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Monitoring
Duration - 12 months
Participants complete questionnaires and provide biological samples to assess quality of life, stress levels, and clinical factors at multiple time points.
3 visits (at baseline, 3 months, and 12 months)
Trial Site Locations
Total: 1 location
1
Department of Neurology, University Hospital Zurich
Zurich, Canton of Zurich, Switzerland, 8091
Actively Recruiting
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Research Team
A
Anton Schmick, MD
S
Susanne Wegener, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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Published Research Related To This Trial
Meaning in stroke family caregiving: A literature review.
Jingjun Zhang, Diana T F Lee
https://pubmed.ncbi.nlm.nih.gov/27671537The modifying role of caregiver burden on predictors of quality of life of caregivers of hospitalized chronic stroke patients.
Yeon-Gyu Jeong, Jun-Pyo Myong, Jung-Wan Koo
https://pubmed.ncbi.nlm.nih.gov/26123859Long-term impact of stroke on family caregiver well-being: a population-based case-control study.
William E Haley, David L Roth, Martha Hovater...
https://pubmed.ncbi.nlm.nih.gov/25740862Neurovascular disease in Switzerland: 10-year trends show non-traditional risk factors on the rise and higher exposure in women.
Martin Hänsel, Klaus Steigmiller, Andreas R Luft...
https://pubmed.ncbi.nlm.nih.gov/35661347Assessing health-related quality of life in urology - a survey of 4500 German urologists.
A Schmick, M Juergensen, V Rohde...
https://pubmed.ncbi.nlm.nih.gov/28629351Machine-learning-based outcome prediction in stroke patients with middle cerebral artery-M1 occlusions and early thrombectomy.
Janne Hamann, Lisa Herzog, Carina Wehrli...
https://pubmed.ncbi.nlm.nih.gov/33220140Measurements of acute cerebral infarction: a clinical examination scale.
T Brott, H P Adams, C P Olinger...
https://pubmed.ncbi.nlm.nih.gov/2749846Interobserver agreement for the assessment of handicap in stroke patients.
J C van Swieten, P J Koudstaal, M C Visser...
https://pubmed.ncbi.nlm.nih.gov/3363593FUNCTIONAL EVALUATION: THE BARTHEL INDEX.
F I MAHONEY, D W BARTHEL
https://pubmed.ncbi.nlm.nih.gov/14258950