Actively Recruiting
The Influence of Chest Physiotherapy on Lung Function Parameters in Primary Ciliary Dyskinesia
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-03
29
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Primary ciliary dyskinesia (PCD) is a rare genetic condition that causes problems with the tiny hair-like structures called motile cilia, leading to chronic infections in the upper and lower respiratory tracts. This study is evaluating how chest physiotherapy affects lung function in patients with PCD. The goal is to understand if a session of chest physiotherapy improves lung function and how lung function tests should be standardized when used over time in these patients. Participants receive a 20-minute session of chest physiotherapy performed by a physiotherapist using airway clearance techniques and a positive expiratory pressure (PEP) device. This procedure is designed to help clear mucus from the lungs. The study focuses on measuring lung function before and after this treatment to observe any short-term changes. During the study, participants will undergo lung function tests including spirometry and Multiple Breath Washout (MBW) both before and 30 minutes after chest physiotherapy. Researchers will compare values such as forced expiratory volume in one second (FEV1) and lung clearance index (LCI) to assess changes. The study helps understand the immediate effects of chest physiotherapy on lung function in PCD and its implications for long-term monitoring. The total duration and follow-up details are aligned with these short-term assessments.
CONDITIONS
Brief Title
Chest Physiotherapy and Lung Function in Primary Ciliary Dyskinesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of primary ciliary dyskinesia
- Able to perform spirometry and Multiple Breath Washout tests
- Age greater than 6 years and up to 50 years
You will not qualify if you...
- Currently experiencing an acute exacerbation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single session with assessments before and after treatment within 30 minutes
Participants receive a 20-minute session of chest physiotherapy with a physiotherapist using airway clearance techniques and a PEP device to improve lung function.
1 visit (in-person) including pre- and post-treatment assessments
Trial Site Locations
Total: 1 location
1
University Hospital Gasthuisberg Leuven
Leuven, Belgium, 3000
Actively Recruiting
Research Team
M
Mieke Boon, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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