Actively Recruiting
Led by Radboud University Medical Center · Updated on 2025-04-11
600
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are investigating cognitive variability in children aged 7 to 10 at their first assessment. This observational study aims to understand how cognitive differences vary between individuals, explore the brain, psychological, and environmental factors influencing these differences, and examine the long-term effects and outcomes related to cognitive variability. The study uses advanced methods including experience sampling, longitudinal designs, and deep phenotyping to answer these questions. Participants may take part in either a behavioural or a behavioural with imaging arm. The behavioural arm includes children aged 7 to 10, while the imaging arm is for children aged 8 to 10 at the first assessment. The imaging arm involves MRI scans such as MP-RAGE, diffusion weighted imaging, and functional MRI during cognitive tasks. Assessments are done at baseline and followed up two years later for imaging, with cognitive task reaction times and questionnaire scores tracked through an average of three years. During the study, children will complete various cognitive tasks measuring reaction times in vocabulary, working memory, speed, fluid reasoning, and exploration. Mood and sleep scores are also tracked using smiley sliders. Imaging participants will undergo baseline and follow-up MRI scans with naturalistic viewing and reasoning tasks. Parents will provide questionnaire data and reaction times on cognitive tasks. Researchers will assess cognitive performance, brain activity, psychological traits, and environmental factors to understand cognitive variability and its outcomes over time.
CONDITIONS
COgnitive Dynamics in Early Childhood
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 1 year
Participants undergo baseline cognitive and imaging assessments including MRI scans and behavioral tests.
1 baseline visit (in-person)
Duration - Up to 3 years
Participants are observed over time with repeated cognitive assessments and questionnaires to track changes.
Repeated assessments throughout the study period
Duration - 1 day
Participants complete follow-up cognitive and imaging assessments two years after baseline.
1 follow-up visit (in-person) at two years after baseline
Total: 1 location
1
Radboudumc Department of Cognitive Neuroscience
Nijmegen, Netherlands, 6525 EN
Actively Recruiting
R
Rogier Kievit
I
Ilse Coolen
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Ilse E J I Coolen, Jordy van Langen, Sophie Hofman...
https://pubmed.ncbi.nlm.nih.gov/39060934