Leveraging calcium score CT radiomics for heart failure risk prediction.
Prerna Singh, Ammar Hoori, Joshua Freeze...
https://pubmed.ncbi.nlm.nih.gov/39505933Actively Recruiting
Age: 18Years - 100Years
All Genders
ID04075162
Community Benefit of No-charge Calcium Score Screening Program
Led by University Hospitals Cleveland Medical Center · Updated on 2025-07-18
77000
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the impact of a no-charge calcium score screening program on cardiovascular disease risk assessment and related medical practices. Cardiovascular disease prevention often relies on risk scores to guide treatment, but recent reviews show uncertainty about their effectiveness. Coronary artery calcium (CAC) scoring is a strong risk marker, yet its use is limited due to cost and reimbursement barriers. This study explores whether offering CAC scans for free increases use and affects physician decisions. The study compares two groups of patients undergoing CAC screening: one group receiving the test at a low charge of $99, and another group receiving the test at no cost. University Hospitals began providing the no-charge CAC test in 2017 to improve access. The study observes how these pricing differences influence downstream medical decisions such as statin prescriptions and further testing. Participants receive a CAC CT scan and are then monitored for one year to track outcomes including statin prescriptions, non-invasive and invasive coronary ischemia testing, and coronary revascularization procedures. The study includes adults aged 18 to 100 who had a CAC scan at University Hospitals from January 2014 onward. Researchers evaluate how the cost of CAC testing affects screening uptake and subsequent cardiovascular care over the study period.
CONDITIONS
Brief Title
Community Benefit of No-charge Calcium Score Screening Program
Who Can Participate
Age: 18Years - 100Years
All Genders
Eligibility Criteria
You may qualify if you...
- Received Coronary Artery Calcium (CAC) CT scan at University Hospitals starting in January 1, 2014.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Diagnostic Evaluation
Duration - 1 day
Participants undergo a Coronary Artery Calcium (CAC) CT scan to assess cardiovascular disease risk.
1 visit (in-person)
Long-term Monitoring
Duration - 1 year
Participants are observed for up to 1 year following the CAC scan to monitor statin prescription and cardiovascular testing outcomes.
Follow-up assessments over 1 year
Trial Site Locations
Total: 1 location
1
University Hospitals
Cleveland, Ohio, United States, 44106
Actively Recruiting
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Research Team
S
Sadeer Al-Kindi, M.D.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Published Research Related To This Trial
Enhancing cardiovascular risk prediction through AI-enabled calcium-omics.
Ammar Hoori, Sadeer Al-Kindi, Tao Hu...
https://pubmed.ncbi.nlm.nih.gov/38750142Enhancing cardiovascular risk prediction through AI-enabled calcium-omics.
Ammar Hoori, Sadeer Al-Kindi, Tao Hu...
https://pubmed.ncbi.nlm.nih.gov/37664409Machine learning derived ECG risk score improves cardiovascular risk assessment in conjunction with coronary artery calcium scoring.
Shruti Siva Kumar, Sadeer Al-Kindi, Nour Tashtish...
https://pubmed.ncbi.nlm.nih.gov/36277775Impact of low/no-charge coronary artery calcium scoring on statin eligibility and outcomes in women: The CLARIFY study.
Sadeer Al-Kindi, Nour Tashtish, Imran Rashid...
https://pubmed.ncbi.nlm.nih.gov/36157553Prevalence of thoracic aortic aneurysm in patients referred for no/low-charge coronary artery calcium scoring: Insights from the CLARIFY registry.
Tasveer Khawaja, Scott E Janus, Nour Tashtish...
https://pubmed.ncbi.nlm.nih.gov/36106308