Predicting effective continuous positive airway pressure in Taiwanese patients with obstructive sleep apnea syndrome.
I-Feng Lin, Ming-Lung Chuang, Yu-Fang Liao...
https://pubmed.ncbi.nlm.nih.gov/12833183Actively Recruiting
Age: 18Years +
All Genders
ID07376343
Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea
Led by Thammasat University · Updated on 2026-04-17
150
Participants Needed
2
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating different predictive equations used to estimate the best continuous positive airway pressure (CPAP) settings for patients with obstructive sleep apnea (OSA) in Thailand. This observational study compares these CPAP predictive equations with the traditional in-laboratory manual titration method to find which equation most accurately predicts the optimal CPAP pressure. The study involves adult participants suspected of having OSA who will undergo detailed sleep assessments. Participants will take part in an in-laboratory sleep study using Type 1 polysomnography performed at the Sleep Center of Thammasat University. During the sleep study, sleep technicians will apply various CPAP predictive equations based on previous reliable research to estimate the ideal CPAP pressure needed to manage OSA. This approach will be compared directly with manual CPAP titration conducted in the lab. Throughout the study, participants will undergo sleep testing and monitoring to evaluate the accuracy of the CPAP pressure predictions. Researchers will measure how well the predictive equations match the optimal pressure determined by manual titration at baseline. Participants will be closely observed during the sleep study to gather data on their sleep patterns and breathing. The total participation time corresponds to the duration of the in-laboratory sleep study session.
CONDITIONS
Brief Title
Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Suspected obstructive sleep apnea (OSA)
- Scheduled to undergo an in-laboratory sleep study
- Aged 18 years or older
You will not qualify if you...
- No indication for in-laboratory manual CPAP titration
- Unable to determine optimal CPAP pressure during manual CPAP titration
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - 1 day
Participants undergo an in-laboratory sleep study where sleep technicians estimate optimal CPAP pressure using predictive equations and manual titration.
1 visit (in-person)
Long-term Monitoring
Duration - Up to study completion
Participants are observed to assess the accuracy of CPAP predictive equations in determining optimal pressure.
No additional visits required
Trial Site Locations
Total: 2 locations
1
Faculty of Medicine, Thammasat University
Pathum Thani, Thailand, 12120
Actively Recruiting
2
Narongkorn Saiphoklang
Pathum Thani, Thailand, 12120
Actively Recruiting
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Research Team
N
Narongkorn Saiphoklang, MD
A
Apiwat Pugongchai, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Ming-Lung Chuang, I-Feng Lin, Janine R E Vintch...
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Jiaying Luo, Sichang Xiao, Zhihui Qiu...
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Ahmad A Bamagoos, Shahad A Alshaynawi, Atheer S Gari...
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Matthew R Ebben, Mariya Narizhnaya, Ana C Krieger
https://pubmed.ncbi.nlm.nih.gov/27878543