Early Diagnosis and Monitoring of Obstructive Sleep Apnea Syndrome Using a Digital Model in Public Health A Prospective Observational Study at IRCCS San Raffaele Hospital

What this Trial Is About

Obstructive Sleep Apnea Syndrome OSAS is a common sleep-related breathing disorder affecting 9-38% of the general population, more often men and increasing with age. It causes symptoms such as snoring, excessive daytime sleepiness, fragmented sleep, frequent awakenings often linked to nocturia, and morning headaches. These disruptions can impair cognitive functions like attention, memory, and executive skills over time, and OSAS is connected to a higher risk of neurodegenerative diseases such as Mild Cognitive Impairment and Alzheimers Dementia. Researchers aim to better understand OSASs impact on cognitive decline and identify patients at higher risk for these diseases. This observational study is conducted by IRCCS San Raffaele Hospitals Neurology - Sleep Disorders Center in Milan. It focuses on patients diagnosed with OSAS according to international standards. The study involves monitoring patients over a period of up to three years to collect detailed clinical and neuroimaging data, aiming to identify phenotypes at higher risk for neurodegenerative progression. No experimental treatments are given, as this is an observational model to improve early diagnosis and therapy monitoring. Participants will be followed regularly to gather information on their clinical signs, symptoms, treatment outcomes, and cognitive status. Data collected will support research, improve resource allocation, and optimize care for patients and families. The primary outcome is to characterize patient profiles at higher risk of progressing to neurodegenerative diseases during the three-year follow-up. This study may advance scientific knowledge and public health strategies related to OSAS management and its broader effects.

Multidisciplinary Network OSA Code (Obstructive Apnea Syndrome): Digital Operative Model in Public Health for an Early Diagnosis and Therapy Monitoring