Actively Recruiting
An RCT Between Coronally Advanced Flap (CAF) and Tunneled Coronally Advanced Flap (TCAF) in Combination With Soft Tissue Graft for Multiple Recession Coverage
Led by University Hospital, Ghent · Updated on 2025-10-01
34
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Ghent
Lead Sponsor
M
Mediplus Ltd UK
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating two surgical techniques, coronally advanced flap (CAF) and tunneled coronally advanced flap (TCAF), combined with soft tissue grafts to treat gum recession in the lower front teeth. The study aims to compare the average root coverage each technique achieves both shortly after surgery and over a long term of up to 10 years. This research could help reduce tooth sensitivity, improve appearance, and make oral hygiene easier for participants. Participants will undergo one of the two surgical procedures, randomly assigned to receive either CAF or TCAF. Both methods involve repositioning the gum higher to cover the recession and include taking a small tissue graft from the palate to support and thicken the gum. After surgery, participants will have regular check-ups for up to 10 years and keep a journal to record medication use, pain levels, tooth sensitivity, and other recovery details. During the study, researchers will measure various outcomes including the mean root coverage, complete root coverage, pocket depth, gum thickness, and aesthetic results over the 10-year period. They will also track post-operative pain, treatment time, root sensitivity, and willingness for retreatment. Participants can expect thorough monitoring through clinical visits, evaluations, and questionnaires throughout the long follow-up period.
CONDITIONS
Brief Title
Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Premandibula.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years old
- Good oral hygiene
- Presence of at least 2 recessions in the lower front teeth
- Good general health
You will not qualify if you...
- Smoker
- Pregnant women (assessed at each visit; no X-rays taken if pregnant during follow-up)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single surgical session with follow-up up to 3 months
Participants undergo surgical procedures to treat gum recessions using either the coronally advanced flap with connective tissue graft or the tunneled coronally advanced flap with connective tissue graft.
1 surgery visit and multiple post-operative visits for up to 3 months
Duration - Up to 10 years
Participants are monitored for long-term outcomes including root coverage, gum health, aesthetic results, and sensitivity up to ten years after surgery.
Periodic visits over 10 years
Trial Site Locations
Total: 1 location
1
Department of Periodontology and Implantology of Ghent University
Ghent, Oost-Vlaanderen, Belgium, 9000
Actively Recruiting
Research Team
V
Véronique Prof. Dr. Christiaens
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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