Comparison of Ultrasound-Guided Adductor Canal Block with iPACK Block versus Suprainguinal Fascia Iliaca Block on Postoperative Pain and Stress in Total Knee Arthroplasty Patients

What this Trial Is About

Patients undergoing total knee arthroplasty often face severe pain after surgery, which can delay recovery and lead to complications like infections and longer hospital stays. This research compares two regional anesthesia techniques used to control postoperative pain and reduce opioid use: the Suprainguinal Fascia Iliaca Block and the combination of Adductor Canal Block with iPACK Block. The study aims to evaluate how these methods affect postoperative pain, stress response, and motor function in these patients. The study involves two groups: one group receives the Suprainguinal Fascia Iliaca Block with 30 ml of 0.25% Bupivacaine at the end of surgery, and the other group receives a combination of Adductor Canal Block and iPACK Block, each with 15 ml of 0.25% Bupivacaine. Both procedures are guided by ultrasound. Researchers will compare opioid consumption, pain scores at rest and during movement, time until the first need for pain relief, muscle strength, nausea, recovery quality, and inflammatory markers within 24 hours after surgery. Participants will be monitored closely during the first 24 hours after surgery with assessments of pain, muscle strength, inflammation markers like IL-6 and CRP, and opioid usage. The study uses double-blind randomized methods to ensure unbiased results. Patient recovery quality and side effects such as nausea will also be tracked. The total participation involves the immediate postoperative period up to 24 hours, focusing on early pain control and stress response outcomes.

Comparison of Two Different Regional Anesthetic Methods in Total Knee Arthroplasty Patients